Formylpeptidreceptorer (Formyl peptide receptors)

Formylpeptidreceptorer

En familj av G-proteinkopplade receptorer som ursprungligen identifierades genom dess förmåga att binda N-formylpeptider såsom N-FORMYLMETIONIN LEUCYL-FENYLALANIN. Eftersom N-formylpeptider finns i MITOKONDRIER och BAKTERIER, denna klass av receptorer tros spela en roll för att förmedla cellulära svar på cellulär skada och bakteriell invasion. Emellertid har icke-formylerade peptidligander också hittats för denna receptorklass.

Förklaring på engelska

A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.

Synonym, svenska: Receptorer, formylpeptid

Synonym, engelska: Formyl Peptide Receptors; Peptide Receptors, Formyl; FMLP Receptor; Receptor, FMLP; N-formyl Hexapeptide Receptor; Hexapeptide Receptor, N-formyl; N formyl Hexapeptide Receptor; Receptor, N-formyl Hexapeptide; N-Formylmethionyl Peptide Receptor; N Formylmethionyl Peptide Receptor; Peptide Receptor, N-Formylmethionyl; Receptor, N-Formylmethionyl Peptide; fMet-Leu-Phe Receptor; Receptor, fMet-Leu-Phe; fMet Leu Phe Receptor; Formyl Peptide Receptor; Receptor, Formyl Peptide; Receptor, Chemotactic Peptide; Chemotactic Peptide Receptor; Peptide Receptor, Chemotactic; F-Chemotactic Peptide Receptor; F Chemotactic Peptide Receptor; Receptor, F-Chemotactic Peptide; Chemoattractant Receptor; Receptor, Chemoattractant