Interleukin-12
Ett heterodimert cytokin som stimulerar till produktion av interferon-gamma i T-celler och NK-celler och som även inducerar differentiering av Th1-hjälparceller. Det medverkar till initiering av cellförmedlad immunitet.
Förklaring på engelska
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.
Synonym, svenska:
Synonym, engelska: Natural Killer Cell Stimulatory Factor; IL-12; Cytotoxic Lymphocyte Maturation Factor; IL 12; IL-12 p70; Interleukin-12 p70; Interleukin 12 p70; Interleukin 12; IL12; Edodekin Alfa
| Svensk term | Interleukin-12 |
| Synonym på svenska | |
| Synonym på engelska | Natural Killer Cell Stimulatory Factor; IL-12; Cytotoxic Lymphocyte Maturation Factor; IL 12; IL-12 p70; Interleukin-12 p70; Interleukin 12 p70; Interleukin 12; IL12; Edodekin Alfa |
| Engelsk term | Interleukin-12 |
| MESH ID | D018664 |