Kalgranulin B
En 13,2 kD-medlem i S-100-familjen av kalciumbindande proteiner som kan bilda homo- eller heterokomplex med kalgranulin A och ett flertal andra proteiner. Kalgranulin A/B-heterodimeren är känd som leukocyt L1-antigenkomplex. Kalgranulin B uttrycks i höga halter i granulocyter tidigt under monocytdifferentieringen, och serumnivåerna av kalgranulin B är förhöjda i samband med många inflammatoriska tillstånd, som t ex cystisk fibros.
Förklaring på engelska
A 13.2-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN A and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin B is expressed at high concentrations in GRANULOCYTES during early monocyte differentiation, and serum calgranulin B levels are elevated in many inflammatory disorders such as CYSTIC FIBROSIS.
Synonym, svenska: CABP-P14
Synonym, engelska: CABP-P14; MRP14 Protein; Leukocyte L1 Protein Heavy Chain; Antigen 60B8-A; Antigen 60B8 A; Macrophage-Related Protein-14; Macrophage Related Protein 14; Myeloid Calcium-Binding Protein p14; Myeloid Calcium Binding Protein p14; MRP-14 Protein; MRP 14 Protein; 60B8-A Antigen; 60B8 A Antigen; Antigen, 60B8-A; S100A9 Protein
| Svensk term | Kalgranulin B |
| Synonym på svenska | CABP-P14 |
| Synonym på engelska | CABP-P14; MRP14 Protein; Leukocyte L1 Protein Heavy Chain; Antigen 60B8-A; Antigen 60B8 A; Macrophage-Related Protein-14; Macrophage Related Protein 14; Myeloid Calcium-Binding Protein p14; Myeloid Calcium Binding Protein p14; MRP-14 Protein; MRP 14 Protein; 60B8-A Antigen; 60B8 A Antigen; Antigen, 60B8-A; S100A9 Protein |
| Engelsk term | Calgranulin B |
| MESH ID | D040502 |